

PROGESKIN SERUM
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CUTANEOUS RE-NEW SERUM
Progeskin Serum is expertly formulated to target the visible signs of aging by focusing on two key proteins: Progerin and Klotho. By regulating the synthesis of these proteins, the serum promotes remarkable epidermal rejuvenation, improving skin vitality and reducing the appearance of wrinkles and fine lines.
With consistent use, the serum firms, tones, and plumps the skin, offering a youthful and revitalized appearance. It also stimulates the skin’s internal regeneration process, providing protection against premature aging.
Skin Instant:
For skin showing visible signs of aging, such as wrinkles, sagging, and loss of firmness. Ideal for those seeking to restore skin vitality, smooth out fine lines, and preserve youthful skin for longer.
Benefits:
- Regulates Progerin synthesis to promote epidermal rejuvenation
- Preserves cell longevity by stimulating Klotho protein synthesis
- Restructures the dermis for anti-aging and anti-wrinkle effects
- Improves firmness and elasticity for a more lifted, toned appearance
- Stimulates the skin’s internal regeneration process, ensuring long-term skin health
How to Use:
Apply a few drops of Progeskin Serum onto clean skin, covering the face, neck, and décolleté in gentle upward movements until fully absorbed.
Avoid contact with the eyes.
Use morning and/or evening, as part of your anti-aging routine.
Loshen & Crem’s Recommendation:
Progeskin Serum is your ally in fighting visible signs of aging, preserving youthful skin, and maintaining a firm, toned complexion.
✔ For firmer, smoother skin
If you’re looking for a serum that visibly improves skin firmness, reduces fine lines, and boosts radiance, this serum is ideal for those with signs of aging or loss of skin vitality.
✔ Perfect for those focused on preventing aging
If you want to maintain youthful skin over time, Progeskin Serum promotes cellular longevity and improves the skin’s structure for long-lasting results.
✔ Ideal for those avoiding invasive treatments
If you’re not ready for more aggressive anti-aging treatments, this serum offers a natural solution to promote skin rejuvenation and protect from aging signs.
How to integrate it into a firming routine:
- If skin shows early signs of aging and needs protection → Use with Sérum A-Glyca to prevent glycation and maintain skin’s youthfulness.
- If skin lacks firmness and contour definition → Pair with Crème MSR-H Visage to enhance elasticity and sculpt facial features.
- If skin appears dull and needs revitalization → Follow with Masque Biomagic to boost radiance and refine texture.
Ingredients:
- Centaurea Cyanus Flower Extract: Known for its soothing properties, it helps improve the skin’s overall tone and texture.
- Juglans Regia (Walnut) Seed Extract: Rich in antioxidants, it protects the skin from environmental stress and supports rejuvenation.
- Juglans Regia (Walnut) Shell Extract: Helps to promote skin regeneration and preserve youthful-looking skin.
- Trifluoroacetyl Tripeptide-2: Stimulates collagen production, promoting a firmer, more toned appearance.
- Xanthan Gum: A natural gum used for its hydrating and skin-smoothing properties.
- Dextran & Disodium EDTA: Improve skin hydration and protect skin integrity from environmental damage.
Full Ingredients List:
Water (Aqua), Propylene Glycol, Glycerin, Methylpropanediol, Ethoxydiglycol, Centaurea Cyanus Flower Extract, Juglans Regia (Walnut) Seed Extract, Juglans Regia (Walnut) Shell Extract, Trifluoroacetyl Tripeptide-2, Xanthan Gum, Dextran, Disodium EDTA, Caprylyl Glycol, Benzoic Acid, Sodium Metabisulfite, Sorbic Acid.
Ingredients are subject to change at the manufacturer’s discretion. For the most complete and up-to-date list, refer to the product packaging.
📄 Biologique Recherche Skin Reaction Policy 📄
At Loshen & Crem, we want to ensure you have the best experience possible with our brands. That’s why we highly recommend a consultation with one of our skin experts before purchasing any Biologique Recherche product.
In case of any reaction, Biologique Recherche requires:
- Clear images of the reaction
- The product and lot number (found on the bottom of the box or product)
- Proof of an online consultation with one of our skin experts
If you choose to purchase without a consultation and experience a reaction, we won’t be able to provide a refund. However, we’re always here to help you find the best products for your skin and answer any questions—so don’t hesitate to reach out.
Complimentary sample.
Free Express Shipping with orders over $189.99
Available at our Edmonton Boutique
Ship to Canada only
Returns & Refunds
At Loshen & Crem, we understand that sometimes, even the most carefully chosen product might not be "the one."
- Returns: You have 14 days from delivery to return any unopened and unused products in perfect condition—just as they arrived.
- Refunds: If your return reaches us within 30 days of purchase, you’ll have the choice between a refund or store credit (your preference, naturellement). After 30 days, store credit is your only option. Beyond 40 days, refunds and credits are no longer possible.
Shipping Policy
At Loshen & Crem, we take delivering your skincare treasures très seriously. From Canada to the U.S., we’re here to ensure your beauty cabinet is always well-stocked.
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Free Shipping:
- Canada: Complimentary EXPRESS shipping on orders over $189.99 CAD (after discounts and before taxes).
- United States: Complimentary EXPRESS shipping on orders over $250 USD. We are temporarily pausing USD payments at the moment. Apologies for the inconvenience, and thank you for your understanding!
- During our annual sales, enjoy free EXPEDITED shipping for orders over $250 CAD (or $350 USD).
- For smaller indulgences, shipping is $21.95 CAD within Canada and $30.95 USD to the U.S.
P.S. We ship to P.O. Boxes via Canada Post—but not during strikes. C’est compliqué.
Processing Time:
We aim to dispatch your order within 2 business days, though peak sales and payment verifications may require a touch more patience.
Please note that if you make any changes with the courier after the dispatch, our carrier will charge a $32 fee. In addition, we will have to withdraw the Free Express shipping option from your SkinSkinGlow points account. We appreciate your understanding.
Our processing time starts from the moment your order is successfully submitted and may take up to 2 business days to dispatch your order. However, please be aware that processing and handling time may be extended during peak sale periods. Before we can ship your order, we may need to hold your order for payment verification and confirm your details with your card issuer.
We will do our very best to minimize delays.
Shipping Rates & Delivery Times
Estimated Delivery Times (Canada):
- British Columbia & Alberta: 1–2 business days
- Manitoba & Saskatchewan: 1–2 business days
- Quebec & Ontario: 1–2 business days
- Atlantic Provinces: 1–3 business days
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United States: Delivery times vary by region:
- Zone 1: Eastern States – 3–4 business days
- Zone 2: Central States – 4–5 business days
- Zone 3: Western States – 5 business days
Remote areas may experience longer shipping times.
Please Note: Shipping windows are estimates and not guarantees. Delays may occur due to weather, traffic, or additional verification processes.
Shipping Address Details
For a smooth delivery, please provide all relevant information, including buzzer codes, directional suffixes (North, South, etc.), or special instructions.
- Address Changes: Once your package has left our warehouse, address updates cannot be made. If you need to make changes before dispatch, email us at info@loshen.ca with your order details.
- Carrier Fees: Any changes made with the courier after dispatch will incur a $32 CAD fee, and the Free Express Shipping option will be deducted from your La Crème Points account.
Tracking Your Order
All shipments include tracking information, so you can follow your package from our warehouse to your door. A confirmation email with your tracking number will be sent once your order is dispatched.
Damaged or Lost Packages
- Damaged Parcels: If your order arrives damaged, please contact us at info@loshen.ca with photos and details. We’ll work to resolve the issue promptly.
- Lost or Stolen Packages: If your package is marked "delivered" but hasn’t arrived, please contact the carrier directly to file a claim.
Tips to Avoid Lost or Stolen Packages:
- Opt for a signature upon receipt (required for orders over $350 CAD).
- Have your package delivered to your workplace.
- If you’re not home on the expected delivery date, ask a neighbor to receive your package.
Unclaimed Parcels
If your package is returned to us unclaimed, we’ll issue a refund minus a $23.95 CAD return shipping fee.
Free Samples
We believe every order deserves a little extra care! Expect 1–3 complimentary samples selected by our Skincare Specialists to perfectly complement your order.
Loyalty Rewards: La Crem Points
Earn La Crème Points with every purchase and redeem them for future orders. From time to time, we also offer Free Gifts With Purchase (GWP) for select brands, but these are available only while supplies last.
Clearance Items
Clearance items are FINAL SALE.
These products are offered at up to 75% off due to minor imperfections, nearing expiry dates (noted in descriptions), or other reasons. Returns, refunds, or credits are not available for these items.
At Loshen & Crem, we aim to deliver excellence at every step of your skincare journey, with care and a touch of elegance. Questions? Don’t hesitate to reach out—we’re always happy to assist!
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About Us
Loshen & Cream
Let's be clear, this is not about us. It's about you, it's about your skin health.
We are not your typical online skin care boutique. Although we are a virtual store, all of the experts behind Loshen & Crem are true professionals with an outstanding knowledge of the skin.
We choose the top skincare brands to provide you with the best options for healthy skin.
#Respectyourskin