Volumizing macro ha serum

A next-generation hyaluronic acid serum designed to visibly restore volume, redefine facial contours, and improve overall skin quality. Powered by proprietary HYAsync technology, this advanced formula binds hyaluronic acid with alpha-lipoic acid to help protect, deliver, and sustain hydration within the skin. The result is a complexion that appears fuller, smoother, and more structurally supported over time—without relying on superficial plumping alone.

This is not just hydration. It’s structural support for skin that is beginning to show volume loss, laxity, and textural changes.

Recommended for:

• Skin experiencing volume loss or early sagging
  
• Fine lines and loss of facial definition
  
• Dull, uneven texture and lack of radiance
  
• All skin types, including dehydrated and mature skin

Benefits:

• Visibly plumps and restores the look of fullness
  
• Helps redefine facial contours, especially in the lower face
  
• Improves skin texture, smoothness, and radiance
  
• Supports long-lasting hydration by protecting HA from degradation
  
• Reduces the appearance of fine lines over time
  
• Strengthens the skin barrier and overall skin resilience

How to use:

• Apply 1–2 pumps to clean, dry skin
• Use morning and evening
• Apply to the entire face, avoiding the eye area
  
• Allow to fully absorb before layering other products
• Follow with SPF during the day

Clinical Study:

A single-center, dermatologist-led clinical study was conducted by Skinbetter Science to evaluate the performance of Ampra Volumizing Macro HA Serum when used twice daily.

The study included 65 women aged 45–65 presenting with mild to moderate signs of skin aging, including fine lines, uneven texture, visible sagging, and loss of radiance. Over a 12-week period, participants incorporated the serum into a controlled skincare routine to ensure results reflected the true performance of the formula.

To preserve the integrity of the study, participants completed a structured washout period prior to enrollment. This included discontinuing active skincare such as exfoliating acids (AHAs/BHAs), antioxidants, vitamin C, peptides, and non-prescription retinoids for 4 weeks, and prescription-strength topicals such as tretinoin and hydroquinone for 4 months.

Before beginning the study, participants followed a standardized 2-week skincare reset using only a gentle cleanser (morning and evening), a moisturizer (morning and evening), and SPF (morning). This baseline routine was maintained throughout the duration of the study to ensure results were not influenced by external variables.

This level of control matters. It allows us to look at the results and understand what the formula is truly capable of—on its own, without interference.

Before and After:

Loshen & Crem recommendation:

This is the type of formula we reach for when hydration alone is no longer enough. If your skin is starting to feel less “supported” or you’re noticing subtle changes in contour, this is where you elevate your routine. Pair it with barrier-supporting creams and consistent SPF to protect the results you’re building. Ideal post-treatment or during seasonal transitions when skin needs deeper structural support.

Ingredients:

• HYAsync (HA + Alpha-Lipoic Acid): Enhances delivery and protects hyaluronic acid for longer-lasting hydration and activity
  
• Hydrolyzed Yeast Extract + Polyglucuronic Acid: Biofermented complex that supports hydration, smoothness, and visible lifting
  
• Hydrolyzed Eragrostis Tef Seed Extract: Supports collagen and elasticity for firmer-looking skin
  
• Palmitoyl Tripeptide-38: Targets the extracellular matrix to improve plumpness and smoothness
  
• Niacinamide: Strengthens the skin barrier and improves tone and resilience
  
• Squalane + Jojoba Esters: Reinforce hydration and barrier function

full inci list
Aqua/Water/Eau, Glycerin, Isocetyl Stearoyl Stearate, Niacinamide, Pentylene Glycol, Jojoba Esters, Hydrolyzed Yeast Extract, Squalane, Glycol Palmitate, Cetyl Alcohol, Lecithin, Sodium Methyl Stearoyl Taurate, Sodium Thioctoyl/Formoyl Hyaluronate, Palmitoyl Tripeptide-38, Hydrolyzed Eragrostis Tef Seed Extract, Hydrolyzed Sodium Hyaluronate, Hydroxypropyl Cyclodextrin, Tetrasodium Glutamate Diacetate, Citric Acid, Xanthan Gum, Polyglucuronic Acid, Cetyl Hydroxyethylcellulose, Tocopherol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol